Outcome of Acute Renal Injury in Diabetic Mice with Experimental Endotoxemia: Role of Hypoxia-Inducible Factor-1α

The role of diabetic nephropathy in the outcome of acute renal injury (AKI) is not well defined. Herein we evaluate the outcome of lipopolysaccharide- (LPS-) induced AKI in streptozotocin-induced diabetes, as well as the potential role of Hypoxia Inducible Factor (HIF-1α) in this condition. Although...

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Main Authors: A. Ortega, A. Fernández, M. I. Arenas, P. López-Luna, C. Muñóz-Moreno, I. Arribas, N. Olea, L. García-Bermejo, J. Lucio-Cazana, R. J. Bosch
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2013/254529