Massive Gene Expansion and Sequence Diversification Is Associated with Diverse Tissue Distribution, Regulation and Antimicrobial Properties of Anti-Lipopolysaccharide Factors in Shrimp

Massive Gene Expansion and Sequence Diversification Is Associated with Diverse Tissue Distribution, Regulation and Antimicrobial Properties of Anti-Lipopolysaccharide Factors in Shrimp

Anti-lipopolysaccharide factors (ALFs) are antimicrobial peptides with a central β-hairpin structure able to bind to microbial components. Mining sequence databases for ALFs allowed us to show the remarkable diversity of ALF sequences in shrimp. We found at least seven members of the ALF fa...

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Bibliographic Details
Main Authors: Gabriel Machado Matos, Paulina Schmitt, Cairé Barreto, Natanael Dantas Farias, Guilherme Toledo-Silva, Fanny Guzmán, Delphine Destoumieux-Garzón, Luciane Maria Perazzolo, Rafael Diego Rosa
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Marine Drugs
Subjects:
host defense peptide
antimicrobial peptide
anti-LPS factor
host‒microbe relationship
functional diversity
invertebrate immunity
crustacean
antimicrobial activity
Online Access:http://www.mdpi.com/1660-3397/16/10/381

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http://www.mdpi.com/1660-3397/16/10/381

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