DNA replication is an integral part of the mouse oocyte's reprogramming machinery.

Many of the structural and mechanistic requirements of oocyte-mediated nuclear reprogramming remain elusive. Previous accounts that transcriptional reprogramming of somatic nuclei in mouse zygotes may be complete in 24-36 hours, far more rapidly than in other reprogramming systems, raise the questio...

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Bibliographic Details
Main Authors: Bingyuan Wang, Martin J Pfeiffer, Caroline Schwarzer, Marcos J Araúzo-Bravo, Michele Boiani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4023938?pdf=render