Human TRIB2 Oscillates during the Cell Cycle and Promotes Ubiquitination and Degradation of CDC25C

Human TRIB2 Oscillates during the Cell Cycle and Promotes Ubiquitination and Degradation of CDC25C

Tribbles homolog 2 (TRIB2) is a member of the mammalian Tribbles family of serine/threonine pseudokinases (TRIB1-3). Studies of TRIB2 indicate that many of the molecular interactions between the single Drosophila Tribbles (Trbl) protein and interacting partners are evolutionary conserved. In this st...

Full description

Bibliographic Details
Main Authors: Kai Ling Liang, Roberto Paredes, Ruaidhri Carmody, Patrick A. Eyers, Stefan Meyer, Tommie V. McCarthy, Karen Keeshan
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:International Journal of Molecular Sciences
Subjects:
TRIB2
pseudokinase
CDC25B
CDC25C
dual-specificity phosphatase
ubiquitin proteasome
degradation
cell cycle
Online Access:http://www.mdpi.com/1422-0067/17/9/1378

Internet

http://www.mdpi.com/1422-0067/17/9/1378

Similar Items