Prevention of neointimal formation using miRNA-126-containing nanoparticle-conjugated stents in a rabbit model.

Prevention of neointimal formation using miRNA-126-containing nanoparticle-conjugated stents in a rabbit model.

Despite recent progress with drug-eluting stents, restenosis and thrombosis after endovascular intervention are still major limitations in the treatment of cardiovascular diseases. These problems are possibly caused by inappropriate inhibition of neointimal formation and retardation of re-endothelia...

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Bibliographic Details
Main Authors: Masayasu Izuhara, Yasuhide Kuwabara, Naritatsu Saito, Erika Yamamoto, Daihiko Hakuno, Yasuhiro Nakashima, Takahiro Horie, Osamu Baba, Masataka Nishiga, Tetsushi Nakao, Tomohiro Nishino, Fumiko Nakazeki, Yuya Ide, Masahiro Kimura, Takeshi Kimura, Koh Ono
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5333844?pdf=render

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http://europepmc.org/articles/PMC5333844?pdf=render

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