Cell-SELEX aptamer for highly specific radionuclide molecular imaging of glioblastoma in vivo.

Cell-SELEX aptamer for highly specific radionuclide molecular imaging of glioblastoma in vivo.

Glioblastoma (GBM) is the most frequent and aggressive primary adult brain tumor with poor prognosis. Epidermal growth factor receptor variant III (EGFRvIII) is the most common and highly oncogenic EGFR mutant in GBM. With the aim to generate specific molecular probes able to target EGFRvIII with hi...

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Bibliographic Details
Main Authors: Xidong Wu, Huiyu Liang, Yan Tan, Chao Yuan, Shuji Li, Xiaowen Li, Guiping Li, Yusheng Shi, Xingmei Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3948368?pdf=render

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http://europepmc.org/articles/PMC3948368?pdf=render

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