Brain gene expression profiles of <it>Cln1 </it>and <it>Cln5 </it>deficient mice unravels common molecular pathways underlying neuronal degeneration in NCL diseases

<p>Abstract</p> <p>Background</p> <p>The neuronal ceroid lipofuscinoses (NCL) are a group of children's inherited neurodegenerative disorders, characterized by blindness, early dementia and pronounced cortical atrophy. The similar pathological and clinical profiles...

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Bibliographic Details
Main Authors: Gentile Massimiliano, Cooper Jonathan D, Kopra Outi, Saharinen Juha, von Schantz Carina, Hovatta Iiris, Peltonen Leena, Jalanko Anu
Format: Article
Language:English
Published: BMC 2008-03-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/146