A FRET-based study reveals site-specific regulation of spindle position checkpoint proteins at yeast centrosomes

A FRET-based study reveals site-specific regulation of spindle position checkpoint proteins at yeast centrosomes

The spindle position checkpoint (SPOC) is a spindle pole body (SPB, equivalent of mammalian centrosome) associated surveillance mechanism that halts mitotic exit upon spindle mis-orientation. Here, we monitored the interaction between SPB proteins and the SPOC component Bfa1 by FRET microscopy. We s...

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Bibliographic Details
Main Authors: Yuliya Gryaznova, Ayse Koca Caydasi, Gabriele Malengo, Victor Sourjik, Gislene Pereira
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-05-01
Series:eLife
Subjects:
checkpoint
centrosome/spindle pole body
mitosis
Online Access:https://elifesciences.org/articles/14029

Internet

https://elifesciences.org/articles/14029

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