Teriflunomide preserves peripheral nerve mitochondria from oxidative stress-mediated alterations

Mitochondrial dysfunction is a common pathological hallmark in various inflammatory and degenerative diseases of the central nervous system, including multiple sclerosis (MS). We previously showed that oxidative stress alters axonal mitochondria, limiting their transport and inducing conformational...

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Bibliographic Details
Main Authors: Bimala Malla, Samuel Cotten, Rebecca Ulshoefer, Friedemann Paul, Anja E. Hauser, Raluca Niesner, Helena Bros, Carmen Infante-Duarte
Format: Article
Language:English
Published: SAGE Publishing 2020-08-01
Series:Therapeutic Advances in Chronic Disease
Online Access:https://doi.org/10.1177/2040622320944773