Transcriptome Profiling and Cytological Assessments for Identifying Regulatory Pathways Associated With Diorcinol N-Induced Autophagy in A3 Cells

Transcriptome Profiling and Cytological Assessments for Identifying Regulatory Pathways Associated With Diorcinol N-Induced Autophagy in A3 Cells

Fungal secondary metabolites serve as a rich resource for exploring lead compounds with medicinal importance. Diorcinol N (DN), a fungal secondary metabolite isolated from an endophytic fungus, Arthrinium arundinis, exhibits robust anticancer activity. However, the anticancer mechanism of DN remains...

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Bibliographic Details
Main Authors: Xiao-Long Yuan, Xiu-Qi Li, Kuo Xu, Xiao-Dong Hou, Zhong-Feng Zhang, Lin Xue, Xin-Min Liu, Peng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Pharmacology
Subjects:
acute lymphocytic leukemia
autophagy
diorcinol N
G1/S phase arrest
transcriptome profiling
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.570450/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.570450/full

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