Homology modeling and molecular docking simulation of some novel imidazo[1,2-a]pyridine-3-carboxamide (IPA) series as inhibitors of Mycobacterium tuberculosis

Homology modeling and molecular docking simulation of some novel imidazo[1,2-a]pyridine-3-carboxamide (IPA) series as inhibitors of Mycobacterium tuberculosis

Abstract Background Tuberculosis (TB) remains a serious global health challenge that is caused by Mycobacterium tuberculosis and has killed numerous people. This necessitated the urgent need for the hunt and development of more potent drugs against the fast-emerging extensively drug-resistant (XDR)...

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Bibliographic Details
Main Authors: Mustapha Abdullahi, Shola Elijah Adeniji, David Ebuka Arthur, Abdurrashid Haruna
Format: Article
Language:English
Published: SpringerOpen 2021-01-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Molecular docking
Binding affinity
Active sites
Homology
Modeling
Hydrogen bonds
Online Access:https://doi.org/10.1186/s43141-020-00102-1

Internet

https://doi.org/10.1186/s43141-020-00102-1

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