Integrated Analysis of MicroRNA (miRNA) and mRNA Profiles Reveals Reduced Correlation between MicroRNA and Target Gene in Cancer

Background. Accumulating evidences demonstrated that microRNA-target gene pairs were closely related to tumorigenesis and development. However, the correlation between miRNA and target gene was insufficiently understood, especially its changes between tumor and normal tissues. Objectives. The aim of...

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Bibliographic Details
Main Authors: Xingsong Li, Xiaokang Yu, Yuting He, Yuhuan Meng, Jinsheng Liang, Lizhen Huang, Hongli Du, Xueping Wang, Wanli Liu
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2018/1972606