Influence of complete administration of adjuvant chemotherapy cycles on overall and disease-free survival in locally advanced rectal cancer: post hoc analysis of a randomized, multicenter, non-inferiority, phase 3 trial

Abstract Background A randomized trial demonstrated that capecitabine is at least as effective as fluorouracil in the adjuvant treatment of patients with locally advanced rectal cancer. However, not all patients receive all planned cycles of chemotherapy. Therefore it is of interest how complete or...

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Bibliographic Details
Main Authors: Flavius Sandra-Petrescu, Florian Herrle, Iris Burkholder, Peter Kienle, Ralf-Dieter Hofheinz
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-018-4309-6