Postnatal High-Fat Diet Increases Liver Steatosis and Apoptosis Threatened by Prenatal Dexamethasone through the Oxidative Effect

The objective of this study was to investigate cellular apoptosis in prenatal glucocorticoid overexposure and a postnatal high fat diet in rats. Pregnant Sprague-Dawley rats at gestational days 14 to 21 were administered saline (vehicle) or dexamethasone and weaned onto either a normal fat diet or a...

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Bibliographic Details
Main Authors: Ying-Hsien Huang, Chih-Jen Chen, Kuo-Shu Tang, Jiunn-Ming Sheen, Mao-Meng Tiao, You-Lin Tain, Chih-Cheng Chen, En-Wei Chu, Shih-Wen Li, Hong-Ren Yu, Li-Tung Huang
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/17/3/369