Increased neuronal glutathione and neuroprotection in GTRAP3-18-deficient mice

Increased neuronal glutathione and neuroprotection in GTRAP3-18-deficient mice

Glutathione (GSH) is an important neuroprotective molecule in the brain. The strategy to increase neuronal GSH level is a promising approach to the treatment of neurodegenerative diseases. However, the regulatory mechanism by which neuron-specific GSH synthesis is facilitated remains elusive. Glutam...

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Bibliographic Details
Main Authors: Koji Aoyama, Fan Wang, Nobuko Matsumura, Hiroshi Kiyonari, Go Shioi, Karo Tanaka, Chisato Kinoshita, Kazue Kikuchi-Utsumi, Masahiko Watabe, Toshio Nakaki
Format: Article
Language:English
Published: Elsevier 2012-03-01
Series:Neurobiology of Disease
Subjects:
EAAC1
Glutathione
GTRAP3-18
Neuroprotection
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111003913

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http://www.sciencedirect.com/science/article/pii/S0969996111003913

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