Modulating intestinal mucus barrier for nanoparticles penetration by surfactants

Improving peroral delivery efficiency is always a persistent goal for both small-molecule and macromolecular drug development. However, intestinal mucus barrier which greatly impedes drug-loaded nanoparticles penetration is commonly overlooked. Therefore, in this study, taking fluorescent labeled PL...

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Bibliographic Details
Main Authors: Xin Zhang, Wei Dong, Hongbo Cheng, Meixia Zhang, Yongqiang Kou, Jian Guan, Qiaoyu Liu, Mingyue Gao, Xiuhua Wang, Shirui Mao
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Asian Journal of Pharmaceutical Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087618306469