Can semipermeable membranes coating materials influence in vivo performance for paliperidone tri-layer ascending release osmotic pump tablet: In vitro evaluation and in vivo pharmacokinetics study

Can semipermeable membranes coating materials influence in vivo performance for paliperidone tri-layer ascending release osmotic pump tablet: In vitro evaluation and in vivo pharmacokinetics study

One purpose of this study was to develop a paliperidone (PAL) tri-layer ascending release push–pull osmotic pump (TA-PPOP) tablet which could meet the needs of clinical applications. And another purpose was to investigate whether different coating materials influenced in vivo performance of TA-PPOP....

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Bibliographic Details
Main Authors: Guangjing Li, Yongjun Wang, Hongming Chen, Donglei Leng, Panqin Ma, Yanjie Dong, Lifang Gao, Zhonggui He
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Ascending release
Tri-layer osmotic pump
Paliperidone
Cellulose acetate
Pharmacokinetics
In vitro–in vivo correlation
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087614000981

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http://www.sciencedirect.com/science/article/pii/S1818087614000981

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