Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12

<p>Abstract</p> <p>Background</p> <p>Increased numbers of tumour-associated macrophages correlate with shortened survival in some cancers. The molecular bases of this correlation are not thoroughly understood. Events triggered by CXCL12 may play a part, as CXCL12 drives...

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Bibliographic Details
Main Authors: Damiani Ernesto, Krampera Mauro, Bonifacio Massimiliano, Mauri Pierluigi, Zamò Alberto, Gottardi Michele, Rigo Antonella, Pizzolo Giovanni, Vinante Fabrizio
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/273