Altered Expression of GABAergic Markers in the Forebrain of Young and Adult <i>Engrailed-2</i> Knockout Mice

Altered Expression of GABAergic Markers in the Forebrain of Young and Adult <i>Engrailed-2</i> Knockout Mice

Impaired function of GABAergic interneurons, and the subsequent alteration of excitation/inhibition balance, is thought to contribute to autism spectrum disorders (ASD). Altered numbers of GABAergic interneurons and reduced expression of GABA receptors has been detected in the brain of ASD subjects...

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Bibliographic Details
Main Authors: Giovanni Provenzano, Angela Gilardoni, Marika Maggia, Mattia Pernigo, Paola Sgadò, Simona Casarosa, Yuri Bozzi
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Genes
Subjects:
interneuron
parvalbumin
somatostatin
GABA
receptor
hippocampus
Online Access:https://www.mdpi.com/2073-4425/11/4/384

Internet

https://www.mdpi.com/2073-4425/11/4/384

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