Contactin-1 Is Reduced in Cerebrospinal Fluid of Parkinson’s Disease Patients and Is Present within Lewy Bodies

Contactin-1 Is Reduced in Cerebrospinal Fluid of Parkinson’s Disease Patients and Is Present within Lewy Bodies

Synaptic degeneration is an early phenomenon in Parkinson’s disease (PD) pathogenesis. We aimed to investigate whether levels of synaptic proteins contactin-1 and contactin-2 in cerebrospinal fluid (CSF) of PD patients are reduced compared to dementia with Lewy bodies (DLB) patients and controls and...

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Bibliographic Details
Main Authors: Madhurima Chatterjee, Inger van Steenoven, Evelien Huisman, Linda Oosterveld, Henk Berendse, Wiesje M. van der Flier, Marta Del Campo, Afina W. Lemstra, Wilma D. J. van de Berg, Charlotte E. Teunissen
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biomolecules
Subjects:
contactin
Lewy bodies
cerebrospinal fluid (CSF), biomarker
synaptic degeneration
Parkinson’s disease (PD), dementia with Lewy bodies (DLB)
Online Access:https://www.mdpi.com/2218-273X/10/8/1177

Internet

https://www.mdpi.com/2218-273X/10/8/1177

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