Sex-Specific Mediating Role of Insulin Resistance and Inflammation in the Effect of Adiposity on Blood Pressure of Prepubertal Children.

To evaluate the association between obesity indices and blood pressure (BP) at 4 years of age, in each sex, and to quantify to which extent this association is mediated by inflammation and insulin resistance (IR).We studied 1250 4-year-old children selected from the population-based birth cohort Gen...

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Bibliographic Details
Main Authors: Liane Correia-Costa, Ana Cristina Santos, Milton Severo, António Guerra, Franz Schaefer, Alberto Caldas Afonso, Henrique Barros, Ana Azevedo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4488421?pdf=render