Deletion of Clusterin Protects Cochlear Hair Cells against Hair Cell Aging and Ototoxicity

Hearing loss is a debilitating disease that affects 10% of adults worldwide. Most sensorineural hearing loss is caused by the loss of mechanosensitive hair cells in the cochlea, often due to aging, noise, and ototoxic drugs. The identification of genes that can be targeted to slow aging and reduce t...

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Bibliographic Details
Main Authors: Xiaochang Zhao, Heidi J. Henderson, Tianying Wang, Bo Liu, Yi Li
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2021/9979157