A New Geldanamycin Analogue from Streptomyces hygroscopicus

A new geldanamycin analogue was isolated from Streptomyces hygroscopicus A070101. The structure was elucidated as 11-methoxy-17-formyl-17-demethoxy-18-O-21-O-dihydrogeldanamycin (1) on the basis of extensive 1D and 2D NMR as well as HRESI-MS spectroscopic data analysis. Compound 1 showed considerabl...

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Bibliographic Details
Main Authors: Hao Zhang, Guang-Zhi Sun, Xiang Li, Hong-Yu Pan, Yan-Sheng Zhang
Format: Article
Language:English
Published: MDPI AG 2010-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/15/3/1161/