Silica nanoparticles are less toxic to human lung cells when deposited at the air–liquid interface compared to conventional submerged exposure

Silica nanoparticles are less toxic to human lung cells when deposited at the air–liquid interface compared to conventional submerged exposure

Background: Investigations on adverse biological effects of nanoparticles (NPs) in the lung by in vitro studies are usually performed under submerged conditions where NPs are suspended in cell culture media. However, the behaviour of nanoparticles such as agglomeration and sedimentation in such comp...

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Bibliographic Details
Main Authors: Alicja Panas, Andreas Comouth, Harald Saathoff, Thomas Leisner, Marco Al-Rawi, Michael Simon, Gunnar Seemann, Olaf Dössel, Sonja Mülhopt, Hanns-Rudolf Paur, Susanne Fritsch-Decker, Carsten Weiss, Silvia Diabaté
Format: Article
Language:English
Published: Beilstein-Institut 2014-09-01
Series:Beilstein Journal of Nanotechnology
Subjects:
aerosol
air–liquid interface
dose
silica nanoparticles
toxicity
Online Access:https://doi.org/10.3762/bjnano.5.171

Internet

https://doi.org/10.3762/bjnano.5.171

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