Concurrence of Danish dementia and cataract: insights from the interactions of dementia associated peptides with eye lens alpha-crystallin.

Familial Danish Dementia (FDD) is an autosomal disease, which is distinguished by gradual loss of vision, deafness, progressive ataxia and dementia. Cataract is the first manifestation of the disease. In this article, we demonstrate a specific correlation between the poisoning of the chaperone activ...

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Bibliographic Details
Main Authors: Ira Surolia, Sharmistha Sinha, Debi Prasad Sarkar, P Yadagiri Reddy, G Bhanuprakash Reddy, Avadhesha Surolia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2488398?pdf=render