Effects of the PPAR-γ Agonist Rosiglitazone on Renal Haemodynamics and the Renin-Angiotensin System in Diabetes

Background. Thiazolidinediones (TZD) have been reported to improve early stages of diabetic nephropathy independent of glycaemic control. Since blockade of the renin-angiotensin system (RAS) is known to reduce the risk of nephropathy, we hypothesised that the renal effect of TZDs might be related to...

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Bibliographic Details
Main Authors: M Cecilia Lansang, Caroline Coletti, Sofia Ahmed, Michael S Gordon, Norman K Hollenberg
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2006-09-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2006.028