Effect of neutrophil elastase and its inhibitor EPI-hNE4 on transepithelial sodium transport across normal and cystic fibrosis human nasal epithelial cells
<p>Abstract</p> <p>Background</p> <p>Hyperactivity of the epithelial sodium (Na<sup>+</sup>) channel (ENaC) and increased Na<sup>+ </sup>absorption by airway epithelial cells leading to airway surface liquid dehydration and impaired mucociliary c...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-10-01
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| Series: | Respiratory Research |
| Online Access: | http://respiratory-research.com/content/11/1/141 |