Population-level distribution and putative immunogenicity of cancer neoepitopes

Population-level distribution and putative immunogenicity of cancer neoepitopes

Abstract Background Tumor neoantigens are drivers of cancer immunotherapy response; however, current prediction tools produce many candidates requiring further prioritization. Additional filtration criteria and population-level understanding may assist with prioritization. Herein, we show neoepitope...

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Bibliographic Details
Main Authors: Mary A. Wood, Mayur Paralkar, Mihir P. Paralkar, Austin Nguyen, Adam J. Struck, Kyle Ellrott, Adam Margolin, Abhinav Nellore, Reid F. Thompson
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Cancer
Subjects:
Neoantigens
Neoepitopes
Immunogenicity
Immunotherapy
TCGA
Online Access:http://link.springer.com/article/10.1186/s12885-018-4325-6

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http://link.springer.com/article/10.1186/s12885-018-4325-6

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