A tissue-specific, Gata6-driven transcriptional program instructs remodeling of the mature arterial tree

A tissue-specific, Gata6-driven transcriptional program instructs remodeling of the mature arterial tree

Connection of the heart to the systemic circulation is a critical developmental event that requires selective preservation of embryonic vessels (aortic arches). However, why some aortic arches regress while others are incorporated into the mature aortic tree remains unclear. By microdissection and d...

Full description

Bibliographic Details
Main Authors: Marta Losa, Victor Latorre, Munazah Andrabi, Franck Ladam, Charles Sagerström, Ana Novoa, Peyman Zarrineh, Laure Bridoux, Neil A Hanley, Moises Mallo, Nicoletta Bobola
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
great vessels
neural crest
smooth muscle cells
embryo
transcription
mouse
Online Access:https://elifesciences.org/articles/31362

Internet

https://elifesciences.org/articles/31362

Similar Items