miR‐424‐5p reduces ribosomal RNA and protein synthesis in muscle wasting

miR‐424‐5p reduces ribosomal RNA and protein synthesis in muscle wasting

Abstract Background A loss of muscle mass occurs as a consequence of a range of chronic and acute diseases as well as in older age. This wasting results from an imbalance of protein synthesis and degradation with a reduction in synthesis and resistance to anabolic stimulation often reported features...

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Bibliographic Details
Main Authors: Martin Connolly, Richard Paul, Roser Farre‐Garros, Samantha A. Natanek, Susannah Bloch, Jen Lee, Jose P. Lorenzo, Harnish Patel, Cyrus Cooper, Avan A. Sayer, Stephen J. Wort, Mark Griffiths, Michael I. Polkey, Paul R. Kemp
Format: Article
Language:English
Published: Wiley 2018-04-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Ribosomal RNA synthesis
microRNA
Protein synthesis
Muscle wasting
Online Access:https://doi.org/10.1002/jcsm.12266

Internet

https://doi.org/10.1002/jcsm.12266

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