Bayesian analysis of high-throughput quantitative measurement of protein-DNA interactions.

Transcriptional regulation depends upon the binding of transcription factor (TF) proteins to DNA in a sequence-dependent manner. Although many experimental methods address the interaction between DNA and proteins, they generally do not comprehensively and accurately assess the full binding repertoir...

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Bibliographic Details
Main Authors: David D Pollock, A P Jason de Koning, Hyunmin Kim, Todd A Castoe, Mair E A Churchill, Katerina J Kechris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3206046?pdf=render