Optogenetic inhibition of D1R containing nucleus accumbens neurons alters cocaine- mediated regulation of Tiam1

Optogenetic inhibition of D1R containing nucleus accumbens neurons alters cocaine- mediated regulation of Tiam1

Exposure to psychostimulants results in structural and synaptic plasticity in striatal medium spiny neurons (MSNs). These cellular adaptations arise from alterations in genes that are highly implicated in the rearrangement of the actin cytoskeleton, such as Tiam1. Previous studies have demonstrated...

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Bibliographic Details
Main Authors: Ramesh eChandra, Jeffrey D Lenz, Amy M Gancarz, Dipesh eChaudhury, Gabrielle L Schroeder, Ming-Hu eHan, Joseph F Cheer, David M Dietz, Mary Kay eLobo
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Cocaine
Cytoskeleton
optogenetics
eNpHR3.0
Medium Spiny Neuron
Tiam1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2013.00013/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2013.00013/full

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