Protein Kinase G Is Involved in Acute but Not in Long-Term Regulation of Renin Secretion

Protein Kinase G Is Involved in Acute but Not in Long-Term Regulation of Renin Secretion

Pharmacological inhibition of the renin–angiotensin–aldosterone system (RAAS) is, in combination with diuretics, the first-choice treatment for hypertension, although 10–20% of patients do not respond adequately. Next to the RAAS, the nitric oxide/cGMP/protein kinase G (PKG) system is the second fun...

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Bibliographic Details
Main Authors: Andrea Schramm, Frank Schweda, Maria Luisa S. Sequeira-Lopez, Franz Hofmann, Peter Sandner, Jens Schlossmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Pharmacology
Subjects:
PKG
cGK
cGMP
sGC stimulation
renin
RAAS
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00800/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00800/full

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