A CRISPR knockout screen reveals new regulators of canonical Wnt signaling
Abstract The Wnt signaling pathways play fundamental roles during both development and adult homeostasis. Aberrant activation of the canonical Wnt signal transduction pathway is involved in many diseases including cancer, and is especially implicated in the development and progression of colorectal...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-09-01
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| Series: | Oncogenesis |
| Online Access: | https://doi.org/10.1038/s41389-021-00354-7 |