Cell morphology-based machine learning models for human cell state classification

Abstract Herein, we implement and access machine learning architectures to ascertain models that differentiate healthy from apoptotic cells using exclusively forward (FSC) and side (SSC) scatter flow cytometry information. To generate training data, colorectal cancer HCT116 cells were subjected to m...

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Bibliographic Details
Main Authors: Yi Li, Chance M. Nowak, Uyen Pham, Khai Nguyen, Leonidas Bleris
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-021-00180-y