TNF-α and CD8+ T cells mediate the beneficial effects of nitric oxide synthase-2 deficiency in pulmonary paracoccidioidomycosis.

TNF-α and CD8+ T cells mediate the beneficial effects of nitric oxide synthase-2 deficiency in pulmonary paracoccidioidomycosis.

<h4>Background</h4>Nitric oxide (NO), a key antimicrobial molecule, was previously shown to exert a dual role in paracoccidioidomycosis, an endemic fungal infection in Latin America. In the intravenous and peritoneal models of infection, NO production was associated with efficient fungal...

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Bibliographic Details
Main Authors: Simone Bernardino, Adriana Pina, Maíra Felonato, Tânia A Costa, Eliseu Frank de Araújo, Cláudia Feriotti, Silvia Boschi Bazan, Alexandre C Keller, Katia R M Leite, Vera L G Calich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23936574/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23936574/?tool=EBI

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