Bone marrow p16INK4a-deficiency does not modulate obesity, glucose homeostasis or atherosclerosis development.

<h4>Objective</h4>A genomic region near the CDKN2A locus, encoding p16(INK4a), has been associated to type 2 diabetes and atherosclerotic vascular disease, conditions in which inflammation plays an important role. Recently, we found that deficiency of p16(INK4a) results in decreased infl...

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Bibliographic Details
Main Authors: Kristiaan Wouters, Céline Cudejko, Marion J J Gijbels, Lucia Fuentes, Kadiombo Bantubungi, Jonathan Vanhoutte, Rebecca Dièvart, Charlotte Paquet, Emmanuel Bouchaert, Sarah Anissa Hannou, Florence Gizard, Anne Tailleux, Menno P J de Winther, Bart Staels, Réjane Paumelle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22403661/pdf/?tool=EBI