The anti-obesity effect of FGF19 does not require UCP1-dependent thermogenesis

The anti-obesity effect of FGF19 does not require UCP1-dependent thermogenesis

Objective: Fibroblast growth factor 19 (FGF19) is a postprandial hormone which plays diverse roles in the regulation of bile acid, glucose, and lipid metabolism. Administration of FGF19 to obese/diabetic mice lowers body weight, improves insulin sensitivity, and enhances glycemic control. The primar...

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Bibliographic Details
Main Authors: Patrick J. Antonellis, Brian A. Droz, Richard Cosgrove, Libbey S. O'Farrell, Tamer Coskun, James W. Perfield, II, Steven Bauer, Mark Wade, Tara E. Chouinard, Joseph T. Brozinick, Andrew C. Adams, Ricardo J. Samms
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877819309093

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http://www.sciencedirect.com/science/article/pii/S2212877819309093

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