Reduced 5-Methylcytosine Level as a Potential Progression Predictor in Patients with T1 or Non-Invasive Urothelial Carcinoma

Reduced 5-Methylcytosine Level as a Potential Progression Predictor in Patients with T1 or Non-Invasive Urothelial Carcinoma

This study aims to elucidate the level of DNA methylation in urothelial carcinomas (UCs) using 5-methylcytosine (5-MeC) immunohistochemistry (IHC). We examined the relationship among 5-MeC levels, DNA (cytosine-5)-methyltransferase 1 (DNMT1) immunostaining levels, and clinicopathologic features. Tis...

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Bibliographic Details
Main Authors: Chi-Jung Chung, Chao-Hsiang Chang, Chih-Pin Chuu, Chi-Rei Yang, Yi-Huei Chang, Chi-Ping Huang, Wen-Chi Chen, Mu-Chi Chung, Han Chang
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:International Journal of Molecular Sciences
Subjects:
5-methylcytosine
immunohistochemistry
urothelial carcinoma
DNA (cytosine-5)-methyltransferase 1
Online Access:http://www.mdpi.com/1422-0067/16/1/677

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http://www.mdpi.com/1422-0067/16/1/677

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