Dysregulation of Dopaminergic Regulatory Factors TH, Nurr1, and Pitx3 in the Ventral Tegmental Area Associated with Neuronal Injury Induced by Chronic Morphine Dependence

Dysregulation of Dopaminergic Regulatory Factors TH, Nurr1, and Pitx3 in the Ventral Tegmental Area Associated with Neuronal Injury Induced by Chronic Morphine Dependence

The ventral tegmental area (VTA), a critical portion of the mesencephalic dopamine system, is thought to be involved in the development and maintenance of addiction. It has been proposed that the dopaminergic regulatory factors TH, Nurr1, and Pitx3 are crucial for determining the survival and mainte...

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Bibliographic Details
Main Authors: Weibo Shi, Yaxing Zhang, Guoting Zhao, Songjun Wang, Guozhong Zhang, Chunling Ma, Bin Cong, Yingmin Li
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
chronic morphine dependence
ventral tegmental area
dopaminergic neurons
TH
Nurr1
Pitx3
Online Access:http://www.mdpi.com/1422-0067/20/2/250

Internet

http://www.mdpi.com/1422-0067/20/2/250

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