Urate oxidase purification by salting-in crystallization: towards an alternative to chromatography.

<h4>Background</h4>Rasburicase (Fasturtec® or Elitek®, Sanofi-Aventis), the recombinant form of urate oxidase from Aspergillus flavus, is a therapeutic enzyme used to prevent or decrease the high levels of uric acid in blood that can occur as a result of chemotherapy. It is produced by S...

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Bibliographic Details
Main Authors: Marion Giffard, Natalie Ferté, François Ragot, Mohamed El Hajji, Bertrand Castro, Françoise Bonneté
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21589929/?tool=EBI