Cordycepin Attenuates Neointimal Formation by Inhibiting Reactive Oxygen Species–Mediated Responses in Vascular Smooth Muscle Cells in Rats

Cordycepin Attenuates Neointimal Formation by Inhibiting Reactive Oxygen Species–Mediated Responses in Vascular Smooth Muscle Cells in Rats

We determined the action mechanism of cordycepin, a major bioactive component of Cordyceps militaris, on responses of rat aortic smooth muscle cells (RASMCs) and on vascular disorders, especially neointimal formation. Cordycepin inhibited platelet-derived growth factor-BB (PDGF-BB)-induced RASMCs mi...

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Bibliographic Details
Main Authors: Kyung-Jong Won, Su-Chan Lee, Chang-Kwon Lee, Hwan Myung Lee, So Hee Lee, Zhi Fang, Ok Byung Choi, Meihua Jin, Junghwan Kim, Taekyu Park, Wahn Soo Choi, Si-Kwan Kim, Bokyung Kim
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319312599

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http://www.sciencedirect.com/science/article/pii/S1347861319312599

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