Retroviral Vector Biosafety: Lessons from Sheep

The safety of retroviral-based systems and the possible transmission of replication-competent virus to patients is a major concern associated with using retroviral vectors for gene therapy. While much effort has been put into the design of safe retroviral production methods and effective in vitro mo...

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Bibliographic Details
Main Authors: Anne Van den Broeke, Arsène Burny
Format: Article
Language:English
Published: Hindawi Limited 2003-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/S1110724303209128