Transgenic mice overexpressing miR-137 in the brain show schizophrenia-associated behavioral deficits and transcriptome profiles.

Transgenic mice overexpressing miR-137 in the brain show schizophrenia-associated behavioral deficits and transcriptome profiles.

Schizophrenia is a psychiatric disorder characterized by positive and negative symptoms and cognitive deficits. The exact cause of schizophrenia is still unknown, but substantial evidence indicates that it has a genetic component. Genome wide association studies demonstrate variants within miR-137 h...

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Bibliographic Details
Main Authors: Yuuichi Arakawa, Kazumasa Yokoyama, Shinya Tasaki, Junichi Kato, Kosuke Nakashima, Michiyasu Takeyama, Atsushi Nakatani, Motohisa Suzuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0220389

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https://doi.org/10.1371/journal.pone.0220389

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