Emodin inhibits colon cancer by altering BCL-2 family proteins and cell survival pathways

Emodin inhibits colon cancer by altering BCL-2 family proteins and cell survival pathways

Abstract Background Currently offered therapeutics to treat colon cancer (CoCa) are toxic when given at maximum tolerated dose to achieve optimal clinical response. Hence, less toxic therapeutic intervention is needed to treat CoCa. In this study, we investigated the effect of a natural agent, Emodi...

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Bibliographic Details
Main Authors: Ian T. Saunders, Hina Mir, Neeraj Kapur, Shailesh Singh
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Cancer Cell International
Subjects:
Colon cancer
Emodin
Anthraquinone
Apoptosis
Mitochondria
Bcl-2
Online Access:http://link.springer.com/article/10.1186/s12935-019-0820-3

Internet

http://link.springer.com/article/10.1186/s12935-019-0820-3

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