Fine mapping for Weaver syndrome in Brown Swiss cattle and the identification of 41 concordant mutations across NRCAM, PNPLA8 and CTTNBP2.

Bovine Progressive Degenerative Myeloencephalopathy (Weaver Syndrome) is a recessive neurological disease that has been observed in the Brown Swiss cattle breed since the 1970's in North America and Europe. Bilateral hind leg weakness and ataxia appear in afflicted animals at 6 to 18 months of...

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Bibliographic Details
Main Authors: Matthew McClure, Euisoo Kim, Derek Bickhart, Daniel Null, Tabatha Cooper, John Cole, George Wiggans, Paolo Ajmone-Marsan, Licia Colli, Enrico Santus, George E Liu, Steve Schroeder, Lakshmi Matukumalli, Curt Van Tassell, Tad Sonstegard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3603989?pdf=render