Derivation of adult canine intestinal organoids for translational research in gastroenterology

Derivation of adult canine intestinal organoids for translational research in gastroenterology

Abstract Background Large animal models, such as the dog, are increasingly being used for studying diseases including gastrointestinal (GI) disorders. Dogs share similar environmental, genomic, anatomical, and intestinal physiologic features with humans. To bridge the gap between commonly used anima...

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Main Authors: Lawrance Chandra, Dana C. Borcherding, Dawn Kingsbury, Todd Atherly, Yoko M. Ambrosini, Agnes Bourgois-Mochel, Wang Yuan, Michael Kimber, Yijun Qi, Qun Wang, Michael Wannemuehler, N. Matthew Ellinwood, Elizabeth Snella, Martin Martin, Melissa Skala, David Meyerholz, Mary Estes, Martin E. Fernandez-Zapico, Albert E. Jergens, Jonathan P. Mochel, Karin Allenspach
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Biology
Subjects:
Organoid model
Canine
Enteroid
GI diseases
Translational research
Intestinal stem cell
Online Access:http://link.springer.com/article/10.1186/s12915-019-0652-6

Internet

http://link.springer.com/article/10.1186/s12915-019-0652-6

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