The Role of Mitochondria-Derived Peptides in Cardiovascular Diseases and Their Potential as Therapeutic Targets

The Role of Mitochondria-Derived Peptides in Cardiovascular Diseases and Their Potential as Therapeutic Targets

Mitochondria-derived peptides (MDPs) are small peptides hidden in the mitochondrial DNA, maintaining mitochondrial function and protecting cells under different stresses. Currently, three types of MDPs have been identified: Humanin, MOTS-c and SHLP1-6. MDPs have demonstrated anti-apoptotic and anti-...

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Bibliographic Details
Main Authors: Siarhei A. Dabravolski, Nikita G. Nikiforov, Antonina V. Starodubova, Tatyana V. Popkova, Alexander N. Orekhov
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
mitochondria-derived peptides
cardiovascular diseases
Humanin
MOTS-c
SHLPs
atherosclerosis
Online Access:https://www.mdpi.com/1422-0067/22/16/8770

Internet

https://www.mdpi.com/1422-0067/22/16/8770

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