Metabolomics analysis reveals a modified amino acid metabolism that correlates with altered oxygen homeostasis in COVID-19 patients

Metabolomics analysis reveals a modified amino acid metabolism that correlates with altered oxygen homeostasis in COVID-19 patients

Abstract We identified the main changes in serum metabolites associated with severe (n = 46) and mild (n = 19) COVID-19 patients by gas chromatography coupled to mass spectrometry. The modified metabolic profiles were associated to an altered amino acid catabolism in hypoxic conditions. Noteworthy,...

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Bibliographic Details
Main Authors: José C. Páez-Franco, Jiram Torres-Ruiz, Víctor A. Sosa-Hernández, Rodrigo Cervantes-Díaz, Sandra Romero-Ramírez, Alfredo Pérez-Fragoso, David E. Meza-Sánchez, Juan Manuel Germán-Acacio, José L. Maravillas-Montero, Nancy R. Mejía-Domínguez, Alfredo Ponce-de-León, Alfredo Ulloa-Aguirre, Diana Gómez-Martín, Luis Llorente
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85788-0

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https://doi.org/10.1038/s41598-021-85788-0

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