Development of GMDR-GPU for gene-gene interaction analysis and its application to WTCCC GWAS data for type 2 diabetes.

Although genome-wide association studies (GWAS) have identified a significant number of single-nucleotide polymorphisms (SNPs) associated with many complex human traits, the susceptibility loci identified so far can explain only a small fraction of the genetic risk. Among other possible explanations...

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Bibliographic Details
Main Authors: Zhixiang Zhu, Xiaoran Tong, Zhihong Zhu, Meimei Liang, Wenyan Cui, Kunkai Su, Ming D Li, Jun Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3633958?pdf=render